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The New England Journal of Medicine: Search Results
The New England Journal of Medicine (NEJM) RSS feed -- Search Results. NEJM ( is a weekly general medical journal that publishes new medical research findings, review articles, and editorial opinion on a wide variety of topics of importance to biomedical science and clinical practice.

Tezacaftor?Ivacaftor in Residual-Function Heterozygotes with Cystic Fibrosis
31/12/69 - Cystic fibrosis is a progressive, systemic, life-limiting, autosomal recessive disease that is caused by reduced quantity or function of the cystic fibrosis transmembrane conductance regulator (CFTR) protein due to mutations in the CFTR gene. Loss of chloride transport activity due to defects in…

Case 36-2017: A 30-Year-Old Man with Fatigue, Rash, Anemia, and Thrombocytopenia
31/12/69 - Presentation of Case. Dr. Amy E. Yuan (Medicine): A 30-year-old man was admitted to this hospital during the summer because of fatigue, rash, fevers, anemia, and thrombocytopenia. Three years before this admission, the patient was involved in a motor vehicle accident that resulted in a large…

Tezacaftor?Ivacaftor in Patients with Cystic Fibrosis Homozygous for Phe508del
31/12/69 - Cystic fibrosis is caused by a reduced quantity or function of cystic fibrosis transmembrane conductance regulator (CFTR) protein, owing to mutations in CFTR. A loss of chloride secretion causes impaction of mucus in the airways, gastrointestinal tract, and exocrine organs, with important clinical…

Cause, Pathogenesis, and Treatment of Nonalcoholic Steatohepatitis
31/12/69 - Fatty liver disease is the most common liver disease in the world. About 25% of adults in the United States have fatty livers in the absence of excessive alcohol consumption, a condition termed nonalcoholic fatty liver disease. More than a quarter of adults with nonalcoholic fatty liver disease are…

A Test-and-Not-Treat Strategy for Onchocerciasis in Loa loa?Endemic Areas
31/12/69 - Mass drug administration with regimens containing ivermectin is the main strategy for the elimination of lymphatic filariasis and onchocerciasis. Although ivermectin is generally safe, the distribution of the drug has been associated with serious adverse events in central African countries. Since…

CFTR Modulator Therapy for Cystic Fibrosis
31/12/69 - Cystic fibrosis is a disease of abnormal ion transport through epithelium that results in progressive lung disease as well as the involvement of other organs including the pancreas, gut, and liver. Cystic fibrosis is caused by mutations in the gene encoding the cystic fibrosis transmembrane…

The Promise, Growth, and Reality of Mobile Health ? Another Data-free Zone
31/12/69 - The use of mobile communication technologies to improve the health of individuals and populations ? dubbed "mobile health," or "mHealth" ? has grown dramatically since 2008, when the term mHealth became widely used. The excitement over the use of mHealth technology especially in low- and…

Management of Acute Hip Fracture
31/12/69 - Foreword. This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the authors? clinical recommendations. Stage. A 65-year-old…

Cholera in Yemen ? An Old Foe Rearing Its Ugly Head
31/12/69 - Yemen, a country with a population of approximately 25 million located at the southern tip of the Arabian Peninsula, is now experiencing one of the largest cholera outbreaks in recent history. The outbreak, which began in late October 2016 and is reportedly due to Vibrio cholerae O1, serotype…

Shiga Toxin?Producing E. coli Infections Associated with Flour
31/12/69 - Flour has been a suspected outbreak vehicle for Shiga toxin?producing Escherichia coli (STEC) infections since 2009, when a multistate outbreak of foodborne disease was linked to prepackaged cookie dough. However, flour was not definitively identified as the source of infection in that outbreak or…

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