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The New England Journal of Medicine: Search Results
The New England Journal of Medicine (NEJM) RSS feed -- Search Results. NEJM (http://www.nejm.org) is a weekly general medical journal that publishes new medical research findings, review articles, and editorial opinion on a wide variety of topics of importance to biomedical science and clinical practice.

Disease and Famine as Weapons of War in Yemen
31/12/69 - How can the medical community take stock of the humanitarian disaster in Yemen? The 3-year-old war intermittently garners attention from Western media ? for example, in August, when an air strike on a school bus killed more than 50 civilians, mostly children ? but is woefully underreported relative…

Adolescent Vaping and Nicotine Use in 2017?2018 ? U.S. National Estimates
31/12/69 - To the Editor: A rapid increase in the prevalence of vaping among adolescents has aroused public health concern. Adolescents who "vape" use a device such as an electronic cigarette to inhale a heated aerosol, which typically contains nicotine. In 2017, vaping was the most common use of any…

Randomized Trial of Endoscopic or Open Vein-Graft Harvesting for Coronary-Artery Bypass
31/12/69 - Despite evidence favoring the use of multiple arterial conduits for coronary-artery bypass grafting (CABG), the greater saphenous vein remains the most commonly used conduit worldwide because of its ready availability and ease of use. The two main limitations of vein grafts in myocardial…

Diagnostic Utility of Exome Sequencing for Kidney Disease
31/12/69 - Targeted capture and sequencing of the protein-coding regions of the genome through exome sequencing is increasingly applied as a first-line diagnostic tool in clinical medicine, particularly for the diagnosis of metabolic and neurodevelopmental disorders in children, as well as for the detection…

Hydroxyurea for Children with Sickle Cell Anemia in Sub-Saharan Africa
31/12/69 - Sickle hemoglobinopathies are common and life-threatening genetic disorders. Homozygous hemoglobin S (HbSS) is the most severe genotype, and together with hemoglobin S?0 thalassemia, is called sickle cell anemia. On deoxygenation, erythrocytes become sickle-shaped, rigid, adhesive, and prone to…

The Anti-Trans Memo ? Abandoning Doctors and Patients
31/12/69 - In October 2018, the New York Times reported on an effort under way by the Department of Health and Human Services (HHS) to redefine gender as a "biological, immutable condition determined by a person?s genitalia at birth." If that effort succeeds, it will, at a minimum, restrict federal…

Case 1-2019: A 34-Year-Old Veteran with Multiple Somatic Symptoms
31/12/69 - Presentation of Case. Dr. Timothy J. Petersen: A 34-year-old man was evaluated at this hospital because of headaches, cognitive changes, mood symptoms, flashbacks, chest pain, arm tingling, and gastrointestinal symptoms. The patient had served as a special operations combat medic in the U.S. Army…

The Grace of Denial
31/12/69 - I sat listening to the case presentation about a woman who waited far too long to seek care for advanced breast cancer. By the time she presented for medical evaluation, her right breast was twice the size of her left and hung like a misshapen butternut squash hidden under her blouse. The physical…

Acute Infection and Myocardial Infarction
31/12/69 - Until the early 20th century, the human life expectancy was less than 50 years, and infections were often fatal. Only in the past century have humans, on average, lived long enough for cardiovascular disease to develop regularly and have antimicrobial therapies made survival from infection the…

Hydroxyurea ? An Essential Medicine for Sickle Cell Disease in Africa
31/12/69 - Higher levels of fetal hemoglobin (HbF) ameliorate the clinical course of sickle cell disease. Hydroxyurea, an inhibitor of the enzyme ribonucleoside diphosphate reductase, increases HbF synthesis by erythroid cells (Figure 1). More than 20 years ago, a major clinical trial of hydroxyurea in the…

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