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The New England Journal of Medicine: Search Results in Neurology\Neurosurgery
The New England Journal of Medicine (NEJM) RSS feed -- Search Results in Neurology\Neurosurgery. NEJM ( is a weekly general medical journal that publishes new medical research findings, review articles, and editorial opinion on a wide variety of topics of importance to biomedical science and clinical practice.

Variant Intestinal-Cell Kinase in Juvenile Myoclonic Epilepsy
31/12/69 - Juvenile myoclonic epilepsy is the most common form of genetic generalized epilepsy and the most common cause of seizures among adolescents and young adults. The disorder is distinguished by the clinical features of myoclonus when the patient awakens from sleep after being sleep-deprived or exposed…

Cardiovascular Safety of Febuxostat or Allopurinol in Patients with Gout
31/12/69 - Gout is a chronic illness characterized by hyperuricemia, arthropathy, tophus development, and urolithiasis and is associated with an increased risk of cardiovascular and chronic kidney disease. The risk of cardiovascular events, including death, is substantially higher in people with gout than in…

Case 7-2018: A 25-Year-Old Man with New-Onset Seizures
31/12/69 - Presentation of Case. Dr. Ethan I. Meltzer (Neurology): A 25-year-old man was admitted to this hospital because of new-onset seizures. The patient had been in his usual state of health until 2 days before admission, when episodes of twitching of the head and neck occurred. The first episode…

Antibody-Mediated Encephalitis
31/12/69 - Antibody-mediated encephalitides constitute a group of inflammatory brain diseases that are characterized by prominent neuropsychiatric symptoms and are associated with antibodies against neuronal cell-surface proteins, ion channels, or receptors (Table 1). Common clinical features include a change…

Swell Findings in Hydrogels
31/12/69 - Targeted surgery requires spatial and temporal selectivity, which is an elusive goal; the realization of this goal may be aided by materials that undergo conformational changes in response to remote stimuli. A recent study by Cangialosi et al. is notable in this regard; it shows that a hydrogel…

Thrombectomy for Stroke at 6 to 16 Hours with Selection by Perfusion Imaging
31/12/69 - Endovascular thrombectomy has been shown to be effective for the treatment of acute ischemic stroke in patients with occlusion of the first segment of the middle cerebral artery or occlusion of the internal carotid artery if treatment is initiated within 6 hours. The results of the recently…

Controlling the Swing of the Opioid Pendulum
31/12/69 - Mr. P. is a 34-year-old man who sees his primary care physician regularly for chronic spine pain. Several years ago, he had a motorcycle accident that left him with a ruptured spleen, a shattered pelvis, and multiple thoracic vertebral fractures. After a prolonged hospital and rehab course, he was…

Placing a Lumbar Epidural Catheter
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Case 5-2018: A 63-Year-Old Man with Confusion after Stem-Cell Transplantation
31/12/69 - Presentation of Case. Dr. Joshua A. Cohen (Medicine): A 63-year-old man was admitted to this hospital with confusion and weakness 5 months after he had undergone allogeneic stem-cell transplantation for chronic lymphocytic leukemia (CLL). The patient had been generally well until 2 years before…

Nusinersen versus Sham Control in Later-Onset Spinal Muscular Atrophy
31/12/69 - Spinal muscular atrophy (SMA) is an autosomal recessive neuromuscular disorder that is characterized by atrophy and weakness of the skeletal muscles of the limbs and trunk and of the bulbar and respiratory muscles. It is caused by homozygous deletions or loss-of-function mutations in the gene…

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