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The New England Journal of Medicine: Search Results in Neurology\Neurosurgery
The New England Journal of Medicine (NEJM) RSS feed -- Search Results in Neurology\Neurosurgery. NEJM ( is a weekly general medical journal that publishes new medical research findings, review articles, and editorial opinion on a wide variety of topics of importance to biomedical science and clinical practice.

Case 36-2017: A 30-Year-Old Man with Fatigue, Rash, Anemia, and Thrombocytopenia
31/12/69 - Presentation of Case. Dr. Amy E. Yuan (Medicine): A 30-year-old man was admitted to this hospital during the summer because of fatigue, rash, fevers, anemia, and thrombocytopenia. Three years before this admission, the patient was involved in a motor vehicle accident that resulted in a large…

Case 35-2017: A 57-Year-Old Woman with Hypoesthesia and Weakness in the Legs and Arms
31/12/69 - Presentation of Case. Dr. Daniel B. Rubin (Neurology): A 57-year-old-woman was admitted to this hospital because of progressive hypoesthesia, paresthesia, and weakness in the arms and legs. The patient had been in her usual health until 18 months before this admission, when paresthesia developed in…

An Unusual Cause of Leg Pain
31/12/69 - A 67-year-old woman presented to her primary care physician with pain in her legs. Approximately 7 weeks earlier, she had noticed a cramping sensation in the back of both thighs and both calves that occurred after walking a couple of blocks and was relieved with rest. . . .

Lomustine and Bevacizumab in Progressive Glioblastoma
31/12/69 - No standard of care has been established for patients with progressive glioblastoma. Previous studies suggested that bevacizumab, a monoclonal antibody that targets vascular endothelial growth factor, is safe and produces responses that result in a decreased use of glucocorticoids and increased…

Thrombectomy 6 to 24 Hours after Stroke with a Mismatch between Deficit and Infarct
31/12/69 - Previous randomized trials that involved patients with acute stroke showed that endovascular thrombectomy had a clinical benefit when it was performed within 6 hours after the onset of stroke symptoms and that the benefit diminished as the interval between the time that the patient was last known…

A New DAWN for Imaging-Based Selection in the Treatment of Acute Stroke
31/12/69 - Two years ago, the publication of the MR CLEAN trial (Multicenter Randomized Clinical Trial of Endovascular Treatment for Acute Ischemic Stroke in the Netherlands), which investigated endovascular mechanical thrombectomy for the treatment of acute ischemic stroke, was called "a first step in the…

Case 34-2017: A 76-Year-Old Man with Fever, Weight Loss, and Weakness
31/12/69 - Presentation of Case. Dr. Benjamin R. Robbins (Psychiatry): A 76-year-old man was admitted to this hospital in the late summer because of weight loss, generalized weakness, and fever. The patient had been well until 3 weeks before admission, when he began to have decreased energy and poor appetite,…

Single-Dose Gene-Replacement Therapy for Spinal Muscular Atrophy
31/12/69 - Spinal muscular atrophy (SMA) is a severe childhood monogenic disease resulting from loss or dysfunction of the gene encoding survival motor neuron 1 (SMN1). The incidence of this disease is approximately 1 in 10,000 live births, with a carrier frequency of 1 in 54. SMA is characterized by the…

Effects of Spaceflight on Astronaut Brain Structure as Indicated on MRI
31/12/69 - Microgravity during spaceflight occurs when the force of gravity is unbalanced and the net force becomes so weak that virtual weightlessness results. The effects of microgravity on the brain have received attention in relation to a syndrome involving optic-disk edema and elevated intracranial…

Nusinersen versus Sham Control in Infantile-Onset Spinal Muscular Atrophy
31/12/69 - Spinal muscular atrophy is an autosomal recessive neuromuscular disorder that is characterized by progressive muscle atrophy and weakness, with an estimated incidence of 1 in 11,000 live births. Approximately 60% of infants who are born with spinal muscular atrophy have type 1 disease, which is…

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