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The New England Journal of Medicine: Search Results in Neurology\Neurosurgery
The New England Journal of Medicine (NEJM) RSS feed -- Search Results in Neurology\Neurosurgery. NEJM ( is a weekly general medical journal that publishes new medical research findings, review articles, and editorial opinion on a wide variety of topics of importance to biomedical science and clinical practice.

Arteriovenous Malformations of the Brain
31/12/69 - Arteriovenous malformations of the brain are congenital anomalies of the blood vessels that are derived from maldevelopment of the capillary network, allowing direct connections between cerebral arteries and veins. The most common presenting symptoms are cerebral hemorrhage and seizures. Focal…

Efficient Trial Design ? FDA Approval of Valbenazine for Tardive Dyskinesia
31/12/69 - A well-executed development program that addresses both regulatory and clinical requirements is critical for making novel therapeutics available as quickly as possible to patients with unmet medical needs. In the case of valbenazine, which was recently approved by the U.S. Food and Drug…

The Failure of Solanezumab ? How the FDA Saved Taxpayers Billions
31/12/69 - The November 2016 announcement that Eli Lilly?s investigational drug solanezumab failed in a phase 3 clinical trial dashed hopes that it would be a long-anticipated disease-modifying treatment for Alzheimer?s disease. For people living with Alzheimer?s ? along with their relatives and caregivers,…

Fluorescein Guidance in Glioblastoma Resection
31/12/69 - Figure 1.

Case 13-2017: A 41-Year-Old Man with Hearing Loss, Seizures, Weakness, and Cognitive Decline
31/12/69 - Presentation of Case. Dr. Haatem M. Reda: A 41-year-old man was seen in the neurology clinic of this hospital because of seizures, weakness, and cognitive decline. The patient had a history of migraine headaches, sensorineural hearing loss, and chronic proteinuria. He had been in his usual health…

Overexpression of the Cytokine BAFF and Autoimmunity Risk
31/12/69 - Multiple sclerosis and systemic lupus erythematosus (SLE) are autoimmune diseases caused by largely unknown environmental factors acting in genetically susceptible persons. Genomewide association studies have provided statistical support for more than 110 independent signals for multiple sclerosis…

A BAFFling Association between Malaria Resistance and the Risk of Multiple Sclerosis
31/12/69 - B cells are increasingly recognized as a therapeutic target in autoimmune diseases. B-cell?depleting therapy with the use of rituximab, a monoclonal antibody to CD20, is approved for the treatment of rheumatoid arthritis and antineutrophil cytoplasmic antibody?associated vasculitis and is…

Zika Virus Infection and Associated Neurologic Disorders in Brazil
31/12/69 - To the Editor: The first cases of a new illness involving fever and rash that was deemed to have been caused by Zika virus (ZIKV) infection in Brazil were reported in 2014, and the presence of the virus was confirmed in April 2015. In October 2015, an unusual increase in the number of cases of…

Addressing the Opioid Epidemic ? Opportunities in the Postmarketing Setting
31/12/69 - The Food and Drug Administration (FDA) recently developed a multipart action plan in response to the opioid epidemic. As part of that initiative, it invited recommendations from the National Academy of Medicine about a regulatory framework that might allow public health considerations to be…

Autochthonous Japanese Encephalitis with Yellow Fever Coinfection in Africa
31/12/69 - To the Editor: Japanese encephalitis virus and yellow fever virus are mosquito-borne flaviviruses that circulate in disjunct geographic areas with different mosquito vectors. Japanese encephalitis is endemic to most of Asia and the Western Pacific, whereas yellow fever occurs in tropical areas of…

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