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The New England Journal of Medicine: Search Results in Neurology\Neurosurgery
The New England Journal of Medicine (NEJM) RSS feed -- Search Results in Neurology\Neurosurgery. NEJM ( is a weekly general medical journal that publishes new medical research findings, review articles, and editorial opinion on a wide variety of topics of importance to biomedical science and clinical practice.

Antiplatelet Therapy after Ischemic Stroke or TIA
31/12/69 - Antiplatelet therapy is the mainstay for the prevention of primary stroke in patients with risk factors and for the prevention of recurrent stroke after transient ischemic attack (TIA) or ischemic stroke. An outstanding question concerns appropriate antiplatelet regimens under various clinical…

The FDA and the Next Wave of Drug Abuse ? Proactive Pharmacovigilance
31/12/69 - In response to the opioid crisis, the Food and Drug Administration (FDA) has taken action on multiple fronts. We have approved better measures for treating opioid use disorder and preventing deaths from overdose, have launched efforts to inform more appropriate prescribing as a way to limit…

Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA
31/12/69 - The risk of ischemic stroke ranges from 3 to 15% in the 90 days after a minor ischemic stroke or a transient ischemic attack (TIA). In several trials, aspirin has been shown to reduce the risk of recurrent stroke by approximately 20%. Clopidogrel blocks platelet aggregation through the…

Case 22-2018: A 64-Year-Old Man with Progressive Leg Weakness, Recurrent Falls, and Anemia
31/12/69 - Presentation of Case. Dr. Molly E. Wolf (Medicine): A 64-year-old man was admitted to this hospital because of progressive leg weakness, recurrent falls, and anemia. The patient had been in his usual state of health until 8 months before this admission, when fatigue on exertion and subjective leg…

Cryptococcus neoformans Meningoencephalitis
31/12/69 - A 36-year-old man presented to the emergency department with a 2-week history of fever, headache, drowsiness, and photophobia. He was previously healthy and was sexually active with men. The physical examination was notable for a temperature of 38.3°C and neck stiffness. Computed tomography of the…

Psychotic Disorders
31/12/69 - The term "psychosis," which is derived from the Greek word for abnormal condition of the mind, has been used in many different ways in clinical medicine. Before 1980, the term "psychotic" was applied generically to persons whose mental functioning was sufficiently impaired to interfere with their…

Parenteral Opioid Shortage ? Treating Pain during the Opioid-Overdose Epidemic
31/12/69 - The opioid-overdose epidemic now causes more than 30,000 deaths per year in the United States. In response to the increasing death toll, many measures have recently been implemented, including reclassification of hydrocodone as a Schedule II opioid and new requirements for physician review of…

Exploiting Viruses to Treat Diseases
31/12/69 - Viruses have evolved to cause both indolent and explosive disease outbreaks, with millions of people infected with the human immunodeficiency virus and hepatitis viruses and with the current outbreaks of Ebola, yellow fever, and Zika viruses in various parts of the world. As a result of intense…

Recurrent Glioblastoma Treated with Recombinant Poliovirus
31/12/69 - Despite aggressive therapy, survival after a diagnosis of World Health Organization (WHO) grade IV malignant glioma is usually less than 20 months, and patients with recurrence usually survive less than 12 months. For decades, research efforts have focused on advancing surgical and radiation…

Case 21-2018: A 61-Year-Old Man with Grandiosity, Impulsivity, and Decreased Sleep
31/12/69 - Presentation of Case. Dr. Samuel J. Boas (Psychiatry): A 61-year-old man was brought to the emergency department of this hospital by his family because of concerns about grandiosity, impulsivity, decreased sleep, and increased alcohol use. The patient had a history of alcohol-use disorder; he had…

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