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The New England Journal of Medicine: Search Results in Pulmonary\Critical Care
The New England Journal of Medicine (NEJM) RSS feed -- Search Results in Pulmonary\Critical Care. NEJM ( is a weekly general medical journal that publishes new medical research findings, review articles, and editorial opinion on a wide variety of topics of importance to biomedical science and clinical practice.

Reanalysis of the Crystalloid versus Hydroxyethyl Starch Trial (CHEST)
31/12/69 - To the Editor: In 2012, the results of the Crystalloid versus Hydroxyethyl Starch Trial (CHEST) were published. CHEST was an investigator-initiated, randomized, controlled trial in which 6% hydroxyethyl starch with a molecular weight of 130 kD and a molar substitution ratio of 0.4 (130/0.4,…

Bronchoscopic Removal of an Obstructing Broncholith
31/12/69 - Figure 1.

Salt-and-Pepper Skin Changes
31/12/69 - Figure 1.

Air Pollution and Mortality in the Medicare Population
31/12/69 - The adverse health effects associated with long-term exposure to air pollution are well documented. Studies suggest that fine particles (particles with a mass median aerodynamic diameter of less than 2.5 ?m [PM2.5]) are a public health concern, with exposure linked to decreased life expectancy.…

Air Pollution Still Kills
31/12/69 - In late October 1948, a dense smog descended over the town of Donora, Pennsylvania. The town was home to a zinc plant and a steel mill, both run by the United States Steel Corporation. Susan Gnora, a 62-year-old resident of Donora, started to gasp and cough as the smog descended. She died the next…

First-Line Nivolumab in Stage IV or Recurrent Non?Small-Cell Lung Cancer
31/12/69 - For the past two decades, platinum-based combination chemotherapy has been the standard-of-care, first-line treatment for patients with advanced non?small-cell lung cancer (NSCLC) without mutations that were sensitive to targeted therapy. However, chemotherapy has provided only a moderate benefit,…

Oral Glucocorticoid?Sparing Effect of Benralizumab in Severe Asthma
31/12/69 - Asthma is a common chronic inflammatory disease of the airways that affects an estimated 315 million persons worldwide. Approximately 5 to 10% of persons with asthma have a severe form of disease that is usually managed with high-dose inhaled glucocorticoids and bronchodilators. Within this group,…

Cancer Immunotherapy Trials Not Immune from Imprecise Selection of Patients
31/12/69 - Arguably, no drug class has more radically and rapidly altered the management of non?small-cell lung cancer (NSCLC) than inhibitors of the interaction between programmed death 1 (PD-1) and its ligand PD-L1. By impeding this negative regulatory signal for T-cell response, PD-1 and PD-L1 inhibitors…

State Sepsis Mandates ? A New Era for Regulation of Hospital Quality
31/12/69 - Sepsis is a major cause of illness and death in the United States, affecting more than 1.5 million Americans each year at an annual cost of over $20 billion. To improve outcomes of sepsis, policymakers are increasingly using regulatory mechanisms intended to provide incentives to clinicians and…

Time to Treatment and Mortality during Mandated Emergency Care for Sepsis
31/12/69 - More than 1.5 million cases of sepsis occur in the United States annually, and many patients with sepsis present to the emergency department. International clinical practice guidelines and the Centers for Medicare and Medicaid Services (CMS) recommend the prompt identification of sepsis and…

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