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The New England Journal of Medicine: Search Results in Geriatrics\Aging
The New England Journal of Medicine (NEJM) RSS feed -- Search Results in Geriatrics\Aging. NEJM ( is a weekly general medical journal that publishes new medical research findings, review articles, and editorial opinion on a wide variety of topics of importance to biomedical science and clinical practice.

The Grace of Denial
31/12/69 - I sat listening to the case presentation about a woman who waited far too long to seek care for advanced breast cancer. By the time she presented for medical evaluation, her right breast was twice the size of her left and hung like a misshapen butternut squash hidden under her blouse. The physical…

Walking Away from Conveyor-Belt Medicine
31/12/69 - The phone rings in our emergency department. It?s a call from a community hospital, which is sending us a 70-year-old patient in need of an urgent procedure. His aortic endoprosthesis, inserted a few years back, appears to be out of place. His aortic aneurysm, which had been stable, is much larger…

Fracture Prevention with Zoledronate in Older Women with Osteopenia
31/12/69 - Bisphosphonates are the principal class of medications used in the management of postmenopausal osteoporosis and have been shown to prevent fractures. Prevention of fractures with bisphosphonates has been shown most clearly in patients with osteoporosis, which is defined either by a bone-density T…

Cancer Survivorship
31/12/69 - Advances in cancer screening and early detection, improvements in therapeutics, and supportive care all contribute to decreasing cancer mortality. Figure 1 shows the changing demographic characteristics of the cancer population from 1975 through 2040. There will be an estimated 26 million survivors…

A Not-So-New Treatment for Old Bones
31/12/69 - Low bone mineral density (i.e. a T score below ?2.5) is the current operational definition of osteoporosis. However, low bone mineral density is actually a risk factor for fracture, not a disease marker. Notwithstanding, nearly all osteoporosis treatment algorithms are based on bone mineral…

Substance-Use Disorders in Later Life
31/12/69 - Substance-use disorders have been declared a national public health emergency. Although the rates of substance use are generally lower among older adults than among younger people, this review focuses on older adults. Physiological changes in hepatic metabolism that occur with aging affect the…

Effect of Aspirin on All-Cause Mortality in the Healthy Elderly
31/12/69 - The Aspirin in Reducing Events in the Elderly (ASPREE) trial was a primary prevention trial that was established to investigate whether the daily use of 100 mg of enteric-coated aspirin would prolong the healthy life span of older adults. The trial, which was conducted in Australia and the United…

Effect of Aspirin on Disability-free Survival in the Healthy Elderly
31/12/69 - Several large, randomized trials have shown the efficacy of aspirin for the secondary prevention of cardiovascular disease among persons with a history of coronary heart disease or stroke. The evidence supporting a benefit of aspirin therapy in the primary prevention of cardiovascular or other…

Effect of Aspirin on Cardiovascular Events and Bleeding in the Healthy Elderly
31/12/69 - Dramatic increases in life expectancy over the past century have led to a substantial demographic shift toward an aging society in many countries. Thus, maintaining good health in older persons is an increasingly important public health aim. Cardiovascular diseases are among the principal causes of…

Should Aspirin Be Used for Primary Prevention in the Post-Statin Era?
31/12/69 - Between 1853 and 1897, German chemists learned to efficiently combine sodium salicylate with acetyl chloride to produce acetylsalicylic acid. That compound, trademarked as aspirin, proved to be a remarkable antiinflammatory and antithrombotic agent and one of the most widely used drugs in…

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