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Nejm News Une Mise à Jour The New England Journal of Medicine by Specialties

 


The New England Journal of Medicine: Search Results in Geriatrics\Aging
The New England Journal of Medicine (NEJM) RSS feed -- Search Results in Geriatrics\Aging. NEJM (http://www.nejm.org) is a weekly general medical journal that publishes new medical research findings, review articles, and editorial opinion on a wide variety of topics of importance to biomedical science and clinical practice.

Case 15-2018: An 83-Year-Old Woman with Nausea, Vomiting, and Confusion
31/12/69 - Presentation of Case. Dr. Andrew S. Hoekzema (Medicine): An 83-year-old woman was admitted to this hospital in the winter because of nausea, vomiting, diarrhea, and confusion. One week before admission, rhinorrhea, sore throat, and nonproductive cough developed. The patient felt feverish but did…

Randomized Trial of Verubecestat for Mild-to-Moderate Alzheimer?s Disease
31/12/69 - Alzheimer?s disease is characterized by the deposition of amyloid-beta (A?) aggregates and neurofibrillary tangles in the brain. The amyloid cascade hypothesis proposes that A? aggregates trigger the spreading of tau-related neurofibrillary tangles and subsequent neuronal degeneration. A? is…

Alzheimer?s Disease in Physicians ? Assessing Professional Competence and Tempering Stigma
31/12/69 - Dr. Redd, a 76-year-old practicing physician, sought help for memory loss at an Alzheimer?s disease research center. After being diagnosed with Alzheimer?s, she became distressed when she was instructed to stop working immediately. Abrupt retirement would leave patients in her highly subspecialized…

Trial of Solanezumab for Mild Dementia Due to Alzheimer?s Disease
31/12/69 - The neuropathological hallmarks of Alzheimer?s disease include extracellular plaques containing amyloid beta (A?) and intracellular neurofibrillary tangles containing hyperphosphorylated tau protein, along with synaptic and neuronal losses. The A? hypothesis of the mechanism of Alzheimer?s disease…

Amyloid-Beta Solubility in the Treatment of Alzheimer?s Disease
31/12/69 - There is general agreement that Alzheimer?s disease will become a crisis by the middle of the century. The Alzheimer?s Association estimates that 5 million Americans currently have Alzheimer?s disease and that their loved ones devote nearly 18 billion hours annually toward their care. If…

An Unconscious Patient with a DNR Tattoo
31/12/69 - To the Editor: We present the case of a person whose presumed code-status preference led him to tattoo "Do Not Resuscitate" on his chest. Paramedics brought an unconscious 70-year-old man with a history of chronic obstructive pulmonary disease, diabetes mellitus, and atrial fibrillation to the…

Management of Acute Hip Fracture
31/12/69 - Foreword. This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the authors? clinical recommendations. Stage. A 65-year-old…

Delirium in Hospitalized Older Adults
31/12/69 - Foreword. This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the author?s clinical recommendations. Stage. A 75-year-old…

Romosozumab or Alendronate for Fracture Prevention in Women with Osteoporosis
31/12/69 - Fragility fractures are common and increase morbidity and mortality. Romosozumab (Amgen and UCB Pharma) is a new bone-forming monoclonal antibody that binds to and inhibits sclerostin, with a dual effect of increasing bone formation and decreasing bone resorption. In a randomized, controlled trial,…

Romosozumab ? Promising or Practice Changing?
31/12/69 - Over the past decade, the osteoporosis landscape has changed. Even though more treatment options are available, fewer measurements of bone mass are being performed and fewer prescriptions for antiosteoporosis agents are being written ? the last probably related to concerns about known side effects…

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