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The New England Journal of Medicine: Search Results in Geriatrics\Aging
The New England Journal of Medicine (NEJM) RSS feed -- Search Results in Geriatrics\Aging. NEJM ( is a weekly general medical journal that publishes new medical research findings, review articles, and editorial opinion on a wide variety of topics of importance to biomedical science and clinical practice.

Efficacy of Recombinant Influenza Vaccine in Adults 50 Years of Age or Older
31/12/69 - Reducing the burden of influenza disease requires improved vaccines, and a recombinant influenza vaccine may contribute to this public-health goal. This vaccine contains recombinant hemagglutinin (HA) proteins produced in a serum-free medium by expresSF+ cells. These cells contain recombinant…

Delegalizing Advance Directives ? Facilitating Advance Care Planning
31/12/69 - When Luis Kutner, a human rights lawyer, first proposed the idea of the "living will" in 1969, he conceptualized it as a document establishing a trust, with the patient as the beneficiary and physicians as trustees. Kutner expected that such a document would be signed by two witnesses, notarized,…

Medical Assistance in Dying ? Implementing a Hospital-Based Program in Canada
31/12/69 - An aging population and shifts in Western societies toward secularism, populism, and an emphasis on individual autonomy and personal control have fueled the movement to legalize assisted dying. It has now been legalized in some form in five European countries (the Netherlands, Belgium, Switzerland,…

Aerobic or Resistance Exercise, or Both, in Dieting Obese Older Adults
31/12/69 - More than a third of persons 65 years of age or older in the United States are obese, and this group constitutes a population vulnerable to adverse outcomes, because obesity exacerbates the age-related decline in physical function and causes frailty. However, appropriate management of obesity in…

The Failure of Solanezumab ? How the FDA Saved Taxpayers Billions
31/12/69 - The November 2016 announcement that Eli Lilly?s investigational drug solanezumab failed in a phase 3 clinical trial dashed hopes that it would be a long-anticipated disease-modifying treatment for Alzheimer?s disease. For people living with Alzheimer?s ? along with their relatives and caregivers,…

Who Decides When a Patient Can?t? Statutes on Alternate Decision Makers
31/12/69 - Many patients cannot make their own medical decisions, having lost what is called decisional capacity. The estimated prevalence of decisional incapacity approaches 40% among adult medical inpatients and residential hospice patients and exceeds 90% among adults in some intensive care units. Patients…

Short-Course Radiation plus Temozolomide in Elderly Patients with Glioblastoma
31/12/69 - Glioblastoma is a fatal illness that is associated with a median survival of less than 2 years. Population studies of glioblastoma have shown that survival declines with increasing age, and the incidence of glioblastoma is increasing, especially among the elderly. Older patients have been…

Lessons from Oregon in Embracing Complexity in End-of-Life Care
31/12/69 - Under the incentives of fee-for-service Medicare, the utilization trends among persons with chronic progressive medical illness include more care in the intensive care unit (ICU), more hospitalizations, and often late or no referrals to hospice care (Figure 1). These utilization patterns are…

Learning to Drive ? Early Exposure to End-of-Life Conversations in Medical Training
31/12/69 - As I drove to Carol?s home, I couldn?t help but notice that even her location seemed terminal: it was the last exit off the freeway, at the end of a winding village road, in the bulb of a quiet cul-de-sac. This was the first of three home visits I would make to Carol, part of an assignment for my…

Screening for Colorectal Neoplasia
31/12/69 - Foreword. This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the author?s clinical recommendations. Stage. A 79-year-old…

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