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The New England Journal of Medicine: Search Results in Hematology\Oncology
The New England Journal of Medicine (NEJM) RSS feed -- Search Results in Hematology\Oncology. NEJM ( is a weekly general medical journal that publishes new medical research findings, review articles, and editorial opinion on a wide variety of topics of importance to biomedical science and clinical practice.

Active Surveillance for Low-Risk Cancers ? A Viable Solution to Overtreatment?
31/12/69 - There is wide variation in the intensity of treatment for low-risk cancers, and many patients are at risk for overtreatment. Despite 5-year survival rates that approach 100% among patients with low-risk differentiated thyroid cancer, prostate cancer, and ductal carcinoma in situ (DCIS) of the…

Certain about Dying with Uncertainty
31/12/69 - Mrs. C. a woman with whom we?d had a long-standing patient?physician relationship, one of us for over 25 years, died recently in the 87th year of her life. A woman who had always maintained her cheerful spirit even in the midst of quite trying medical setbacks, she was one of our favorite patients.…

Adjuvant Pertuzumab and Trastuzumab in Early HER2-Positive Breast Cancer
31/12/69 - Combining trastuzumab, an anti?human epidermal growth factor receptor 2 (HER2) monoclonal antibody, with adjuvant chemotherapy has markedly improved outcomes among patients with HER2-positive early breast cancer, reducing the risk of disease recurrence and death. The combination of chemotherapy and…

Clonal Hematopoiesis and Risk of Atherosclerotic Cardiovascular Disease
31/12/69 - Aging is associated with an increased incidence of cancer and cardiovascular disease. We and others recently used whole-exome sequencing data to identify a common, age-related disorder marked by an expansion of hematopoietic clones carrying recurrent somatic mutations, most frequently…

Case 21-2017: A 28-Year-Old Pregnant Woman with Endocervical Carcinoma
31/12/69 - Presentation of Case. Dr. Mariam Naqvi (Obstetrics and Gynecology): A 28-year-old pregnant woman with Rh isoimmunization and endocervical carcinoma was seen in the maternal?fetal outpatient clinic of this hospital at 34.1 weeks of gestation. The patient was gravida 3, para 2001 (the first delivery…

Follow-up of Prostatectomy versus Observation for Early Prostate Cancer
31/12/69 - We previously reported that radical prostatectomy was not associated with significantly lower all-cause or prostate-cancer mortality than observation with noncurative palliative interventions through 12 years among men with localized prostate cancer detected during the early era of…

CHIP-ping Away at Atherosclerosis
31/12/69 - Efforts at prevention of cardiovascular disease hinge on the concept of risk factors that, when treated, attenuate the incidence of the disease. Since the concept of cardiovascular risk factors was first proposed in the Framingham Heart Study, many distinct risk algorithms have been developed to…

Questioning Our APHINITY for More
31/12/69 - The initial report of the effect of human epidermal growth factor receptor 2 (HER2) amplification on the risk of relapse and death from breast cancer ushered in the modern world of "targeted" therapy, and research moved quickly from target identification to therapeutic exploitation. Trastuzumab,…

The Economics of Indication-Based Drug Pricing
31/12/69 - Pharmaceutical treatments and medical devices often have varying effectiveness depending on the indication for which they?re used: in oncology, for instance, response to a treatment varies with the type of tumor and stage of disease. The advent and proliferation of precision medicine in which…

Idarucizumab for Dabigatran Reversal ? Full Cohort Analysis
31/12/69 - Patients who are receiving oral anticoagulant therapy for the prevention or treatment of thrombosis may benefit from anticoagulant reversal if they present with life-threatening bleeding or if they will be undergoing urgent surgery or intervention. Therefore, the availability of specific reversal…

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