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Nejm News Une Mise à Jour The New England Journal of Medicine by Specialties

 


The New England Journal of Medicine: Search Results in Hematology\Oncology
The New England Journal of Medicine (NEJM) RSS feed -- Search Results in Hematology\Oncology. NEJM (http://www.nejm.org) is a weekly general medical journal that publishes new medical research findings, review articles, and editorial opinion on a wide variety of topics of importance to biomedical science and clinical practice.

Hemoglobinopathies in the Fetal Position
31/12/69 - The hemoglobinopathies, disorders that are caused by mutations in genes that encode the "adult" globins, exert a devastating toll on patients and their families. Worldwide, approximately 300,000 babies are born with sickle cell disease and 60,000 are born with ?-thalassemia each year. However, if…

Case 33-2018: A 57-Year-Old Man with Confusion, Fever, Malaise, and Weight Loss
31/12/69 - Presentation of Case. Dr. Joshua A. Cohen (Medicine): A 57-year-old man presented to this hospital with confusion, cough, fever, and unintentional weight loss. The patient had been in his usual state of health until approximately 7 weeks before this presentation, when malaise and anorexia…

Aplastic Anemia
31/12/69 - Aplastic anemia is a disease with a long history. The first case description was published by Paul Ehrlich in 1888, the term "anemia aplastique" originated with Louis Henri Vaquez in 1904, and clinical features were described by Richard C. Cabot and other pathologists in the early 20th century.…

Allogeneic BK Virus?Specific T Cells for Progressive Multifocal Leukoencephalopathy
31/12/69 - Progressive multifocal leukoencephalopathy (PML) is a rare demyelinating infection of the central nervous system caused by reactivation of the JC polyomavirus that occurs in the context of defective cellular immunity. Common underlying conditions that are associated with JC virus infection include…

National Coverage Analysis of CAR-T Therapies ? Policy, Evidence, and Payment
31/12/69 - In December 2017, the Boston radio station WBUR chronicled the case of the first patient at Massachusetts General Hospital to receive axicabtagene ciloleucel (Yescarta, Gilead) outside a clinical trial. The chimeric antigen receptor T cells (CAR-Ts) were made from 71-year-old Barbara Kearney?s own…

Venetoclax in a Patient with a Blastic Plasmacytoid Dendritic-Cell Neoplasm
31/12/69 - To the Editor: A blastic plasmacytoid dendritic-cell neoplasm is a rare tumor with very aggressive clinical behavior and no established treatment. Available treatment options include aggressive multiagent chemotherapeutic regimens. Treatment for relapsed disease is largely ineffective, and the…

Neuroblastoma and Histone Demethylation
31/12/69 - Neuroblastoma is a childhood cancer of the sympathetic nervous system, with a propensity for widespread metastasis and aggressive clinical behavior. For patients with so-called high-risk disease (typically patients 18 months of age or older who present with metastatic disease), standard therapy is…

Radial Fracture Due to Parathyroid Carcinoma
31/12/69 - Figure 1.

Classification and Personalized Prognosis in Myeloproliferative Neoplasms
31/12/69 - Myeloproliferative neoplasms are clonal hematopoietic disorders comprising polycythemia vera, which is characterized by red-cell overproduction; essential thrombocythemia, which involves elevated platelet counts; and myelofibrosis, which is defined by bone marrow fibrosis. Polycythemia vera and…

Brigatinib versus Crizotinib in ALK-Positive Non?Small-Cell Lung Cancer
31/12/69 - Rearrangements of the oncogenic anaplastic lymphoma kinase (ALK) gene occur in 3 to 5% of patients with non?small-cell lung cancer (NSCLC). A previous phase 3 trial showed that progression-free survival was significantly longer among patients who received crizotinib, a first-generation ALK…

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