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Nejm News Une Mise à Jour The New England Journal of Medicine by Specialties

 


The New England Journal of Medicine: Search Results in Hematology\Oncology
The New England Journal of Medicine (NEJM) RSS feed -- Search Results in Hematology\Oncology. NEJM (http://www.nejm.org) is a weekly general medical journal that publishes new medical research findings, review articles, and editorial opinion on a wide variety of topics of importance to biomedical science and clinical practice.

Midostaurin plus Chemotherapy for Acute Myeloid Leukemia with a FLT3 Mutation
31/12/69 - Acute myeloid leukemia (AML) is a heterogeneous disease that remains challenging to treat because of patient factors (age and coexisting diseases) and intrinsic biologic factors. Cytogenetic and mutational data are used to divide patients into subgroups defined according to prognostic factors and…

Case 19-2017 ? A 53-Year-Old Woman with Leg Numbness and Weakness
31/12/69 - Presentation of Case. Dr. Kristyn M. Spera (Neurology): A 53-year-old woman with rheumatoid arthritis was admitted to this hospital because of progressive asymmetric hypoesthesia and weakness in the legs. The patient had been in her usual health until 4 months before this admission, when…

First-Line Nivolumab in Stage IV or Recurrent Non?Small-Cell Lung Cancer
31/12/69 - For the past two decades, platinum-based combination chemotherapy has been the standard-of-care, first-line treatment for patients with advanced non?small-cell lung cancer (NSCLC) without mutations that were sensitive to targeted therapy. However, chemotherapy has provided only a moderate benefit,…

Cancer Immunotherapy Trials Not Immune from Imprecise Selection of Patients
31/12/69 - Arguably, no drug class has more radically and rapidly altered the management of non?small-cell lung cancer (NSCLC) than inhibitors of the interaction between programmed death 1 (PD-1) and its ligand PD-L1. By impeding this negative regulatory signal for T-cell response, PD-1 and PD-L1 inhibitors…

Perirenal Extramedullary Hematopoiesis
31/12/69 - Figure 1.

Timing of Metastasis in Breast Cancer
31/12/69 - In 2015, almost 232,000 women in the United States received a diagnosis of invasive breast cancer, and approximately 40,000 women died of metastatic breast cancer. The leading cause of these deaths was metastatic spread. The timing and distribution of breast-cancer metastases vary considerably. In…

Clonal Hematopoiesis and Risk of Atherosclerotic Cardiovascular Disease
31/12/69 - Aging is associated with an increased incidence of cancer and cardiovascular disease. We and others recently used whole-exome sequencing data to identify a common, age-related disorder marked by an expansion of hematopoietic clones carrying recurrent somatic mutations, most frequently…

CHIP-ping Away at Atherosclerosis
31/12/69 - Efforts at prevention of cardiovascular disease hinge on the concept of risk factors that, when treated, attenuate the incidence of the disease. Since the concept of cardiovascular risk factors was first proposed in the Framingham Heart Study, many distinct risk algorithms have been developed to…

Seesaw Nystagmus
31/12/69 - Figure 1.

Completion Dissection or Observation for Sentinel-Node Metastasis in Melanoma
31/12/69 - Sentinel-lymph-node biopsy is a standard procedure in the care of appropriately selected patients with melanoma. The first Multicenter Selective Lymphadenectomy Trial (MSLT-I) confirmed the value of early nodal evaluation and treatment. This prospective, international, randomized trial showed that…

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