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Nejm News Une Mise à Jour The New England Journal of Medicine by Specialties

 


The New England Journal of Medicine: Search Results in Endocrinology
The New England Journal of Medicine (NEJM) RSS feed -- Search Results in Endocrinology. NEJM (http://www.nejm.org) is a weekly general medical journal that publishes new medical research findings, review articles, and editorial opinion on a wide variety of topics of importance to biomedical science and clinical practice.

Canagliflozin and Cardiovascular and Renal Events in Type 2 Diabetes
31/12/69 - Type 2 diabetes mellitus is associated with a substantial risk of cardiovascular and renal disease. The use of inhibitors of sodium?glucose cotransporter 2 (SGLT2) results in favorable effects on biomarkers, including glycemia, blood pressure, weight, intrarenal hemodynamics, and albuminuria, and…

NAD Deficiency, Congenital Malformations, and Niacin Supplementation
31/12/69 - Major congenital malformations occur in at least 2% of human births. There are relatively few identified causes. The origins of most malformations have been difficult to determine and probably involve genetic and environmental factors or gene?environment interaction. Although malformations…

Metabolism and Congenital Malformations ? NAD?s Effects on Development
31/12/69 - We have long known that metabolism must be tightly controlled to support the needs of individual cells and tissues. Nutrient oxidation is necessary for the production of adenosine triphosphate (ATP), which supports energetically unfavorable processes in cells, and for the metabolic conversion of…

Insulin-Mediated Lipohypertrophy
31/12/69 - Figure 1.

Preventing Fat Gain by Blocking Follicle-Stimulating Hormone
31/12/69 - In a recent report, Liu and colleagues presented evidence that follicle-stimulating hormone (FSH) influences thermogenesis and adiposity in mice. They had reported previously that a polyclonal antibody that targets the beta subunit of FSH diminished ovariectomy-induced bone loss in mice. In the…

Active Surveillance for Low-Risk Cancers ? A Viable Solution to Overtreatment?
31/12/69 - There is wide variation in the intensity of treatment for low-risk cancers, and many patients are at risk for overtreatment. Despite 5-year survival rates that approach 100% among patients with low-risk differentiated thyroid cancer, prostate cancer, and ductal carcinoma in situ (DCIS) of the…

Association of Changes in Diet Quality with Total and Cause-Specific Mortality
31/12/69 - Some epidemiologic studies of nutrition focus on dietary patterns rather than single nutrients or foods to evaluate the association between diet and health outcomes. Accumulated evidence supports an association between healthy dietary patterns and a decreased risk of death. Results from recent…

Health Effects of Overweight and Obesity in 195 Countries over 25 Years
31/12/69 - The prevalence of overweight and obesity is increasing worldwide. Epidemiologic studies have identified high body-mass index (BMI, the weight in kilograms divided by the square of the height in meters) as a risk factor for an expanding set of chronic diseases, including cardiovascular disease,…

Global Health Effects of Overweight and Obesity
31/12/69 - The Global Burden of Disease (GBD) study that is now reported in the Journal offers a discouraging reminder that the global obesity epidemic is worsening in most parts of the world and that its implications regarding both physical health and economic health remain ominous. The study, in which…

Thyroid Hormone Therapy for Older Adults with Subclinical Hypothyroidism
31/12/69 - Subclinical hypothyroidism is defined as an elevated serum thyrotropin level and a serum free thyroxine level within the reference range. Between 8% and 18% of adults 65 years of age or older have these biochemical features, and the prevalence is higher among women than among men. Subclinical…

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