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The New England Journal of Medicine: Search Results in Nephrology
The New England Journal of Medicine (NEJM) RSS feed -- Search Results in Nephrology. NEJM ( is a weekly general medical journal that publishes new medical research findings, review articles, and editorial opinion on a wide variety of topics of importance to biomedical science and clinical practice.

Case 19-2018: A 15-Year-Old Girl with Acute Kidney Injury
31/12/69 - Presentation of Case. Dr. Helen I. Healy (Pediatrics): A 15-year-old girl was admitted to this hospital during the summer because of acute kidney injury. The patient had been well until 8 days before admission, when painful cramping in the lower abdomen and bloody diarrhea developed. Bowel…

Restrictive versus Liberal Fluid Therapy for Major Abdominal Surgery
31/12/69 - Each year, at least 310 million patients undergo major surgery worldwide, procedures that involve the administration of intravenous fluids. Clinicians have traditionally administered generous amounts of intravenous fluids perioperatively to correct for preoperative fasting and other fluid deficits,…

Sunitinib Alone or after Nephrectomy in Metastatic Renal-Cell Carcinoma
31/12/69 - Kidney cancer accounts for 5% of all cancers in men and 3% of all cancers in women, and approximately 15% of these are metastatic at diagnosis. More than 15 years ago, randomized, controlled trials showed prolonged survival with initial nephrectomy, as compared with immunotherapy alone, among…

Case 17-2018: A 40-Year-Old Woman with Leg Swelling and Abdominal Distention and Pain
31/12/69 - Presentation of Case. Dr. Molly E. Wolf (Medicine): A 40-year-old woman was evaluated at this hospital because of progressive edema of the legs, as well as abdominal distention and pain. The patient had been in good health until approximately 10 months before this evaluation, when episodes of pain…

Burosumab Therapy in Children with X-Linked Hypophosphatemia
31/12/69 - X-linked hypophosphatemia, a disorder of renal phosphate wasting and the most common heritable form of rickets, is caused by loss-of-function mutations in the gene encoding phosphate-regulating endopeptidase homolog X-linked (PHEX), which results in excess circulating fibroblast growth factor 23…

The Drug-Intoxication Epidemic and Solid-Organ Transplantation
31/12/69 - To the Editor: The drug-abuse epidemic in the United States has led to an increased number of organ donors dying from drug intoxication. We investigated the effect of drug intoxication?related deaths on organ donation and outcomes after transplantation by analyzing data on donors and…

Case 15-2018: An 83-Year-Old Woman with Nausea, Vomiting, and Confusion
31/12/69 - Presentation of Case. Dr. Andrew S. Hoekzema (Medicine): An 83-year-old woman was admitted to this hospital in the winter because of nausea, vomiting, diarrhea, and confusion. One week before admission, rhinorrhea, sore throat, and nonproductive cough developed. The patient felt feverish but did…

Improving the Supply and Quality of Deceased-Donor Organs for Transplantation
31/12/69 - Organ transplantation is the treatment of choice for many patients with end-stage diseases, but the supply of organs that are considered acceptable according to current criteria is limited. Approaches to reducing the increasing gap between demand for and availability of donated organs have focused…

31/12/69 - Calciphylaxis is a rare, life-threatening syndrome of vascular calcification characterized by occlusion of microvessels in the subcutaneous adipose tissue and dermis that results in intensely painful, ischemic skin lesions. Once calciphylaxis has been diagnosed, the prognosis is generally poor…

The Wrong Frame of Mind
31/12/69 - In this Journal feature, information about a real patient is presented in stages (boldface type) to an expert clinician, who responds to the information by sharing relevant background and reasoning with the reader (regular type). The authors? commentary follows. A 62-year-old woman with…

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