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The New England Journal of Medicine: Search Results in Nephrology
The New England Journal of Medicine (NEJM) RSS feed -- Search Results in Nephrology. NEJM ( is a weekly general medical journal that publishes new medical research findings, review articles, and editorial opinion on a wide variety of topics of importance to biomedical science and clinical practice.

Timing of Renal-Replacement Therapy in Patients with Acute Kidney Injury and Sepsis
31/12/69 - Acute kidney injury is a frequent complication in patients hospitalized in the intensive care unit (ICU) for septic shock and is associated with high mortality. Acute kidney injury associated with sepsis is characterized by a distinct pathophysiology, and patients with acute kidney injury and…

Fatal Encephalitic Borna Disease Virus 1 in Solid-Organ Transplant Recipients
31/12/69 - To the Editor: Borna disease virus 1 (BoDV-1; species Mammalian 1 orthobornavirus) causes progressive meningoencephalitis, mainly in horses and sheep. Evidence of BoDV-1 infection in humans is limited. However, after the identification of a bornavirus transmitted by exotic pet squirrels ? the…

Dialysis-Facility Joint-Venture Ownership ? Hidden Conflicts of Interest
31/12/69 - Since 1972, when the U.S. government began covering the costs of dialysis for nearly all Americans with end-stage renal disease (ESRD), dialysis has become big business. In 2015, the Centers for Medicare and Medicaid Services (CMS) spent roughly $34 billion on its beneficiaries with ESRD. In recent…

Antibody-Mediated Rejection of Solid-Organ Allografts
31/12/69 - End-stage organ diseases are responsible for millions of deaths worldwide each year. Organ transplantation has become the treatment of choice, but despite the 120,000 new organ transplantations performed each year, only 1 million persons worldwide have functioning solid-organ transplants because of…

Uremic Frost in End-Stage Renal Disease
31/12/69 - A 39-year-old man with end-stage renal disease presented to the emergency department with anorexia, nausea, vomiting, and oliguria. Five months earlier, he had stopped attending his regular hemodialysis sessions; he reported that he had thought that the sessions were not needed because he continued…

Case 24-2018: A 71-Year-Old Man with Acute Renal Failure and Hematuria
31/12/69 - Presentation of Case. Dr. Joshua Z. Drago (Medicine): A 71-year-old man was transferred to this hospital because of worsening renal function and hematuria. Three weeks before this admission, the patient?s wife became ill with chills, fatigue, and myalgias, and she thought she had influenza. A few…

Cytoreductive Nephrectomy ? Patient Selection Is Key
31/12/69 - Metastatic renal-cell carcinoma has diverse clinical presentations ranging from incidental detection to a highly symptomatic systemic illness. Patients with metastatic renal-cell carcinoma are assigned a risk category ? favorable, intermediate, or poor ? on the basis of two published models…

A Reliable Diagnostic Test for Hypotonic Polyuria
31/12/69 - Pinpointing the cause of hypotonic polyuria in a patient poses a diagnostic and therapeutic challenge, particularly in distinguishing primary polydipsia (either psychogenic or nonpsychogenic) from partial pituitary insufficiency due to injury or neoplasm. Diabetes insipidus is one cause of…

A Copeptin-Based Approach in the Diagnosis of Diabetes Insipidus
31/12/69 - The determination of a specific diagnosis in patients with polyuria and low plasma osmolality (i.e. hypotonic polyuria) is a frequent problem in clinical practice. In the absence of osmotic diuresis, polyuria can result from one of three fundamentally different conditions: insufficient production…

Sunitinib Alone or after Nephrectomy in Metastatic Renal-Cell Carcinoma
31/12/69 - Kidney cancer accounts for 5% of all cancers in men and 3% of all cancers in women, and approximately 15% of these are metastatic at diagnosis. More than 15 years ago, randomized, controlled trials showed prolonged survival with initial nephrectomy, as compared with immunotherapy alone, among…

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